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Novel radiation therapy techniques: An outcome based discussion

Novel radiation therapy techniques: An outcome based discussion

Novel radiation therapy techniques: An outcome based discussion

Veterinary Cancer Society
Veterinary Cancer Society
on behalf of Missouri Veterinary Medical Association


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Normal Price: FREE $25.00


Launch date: 22 Dec 2016
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Last updated: 10 Feb 2017

Reference: 167574

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Over the last 20 years an amazing transformation has occurred in the management of human cancers. Advanced imaging, including PET-CT has improved the ability to diagnose, stage and monitor disease. Advances in radiation planning and dose delivery including intensity modulated radiation therapy (IMRT) allows dose to be “painted” onto the tumor while sparing surrounding normal tissues. IMRT has improved tumor control for many types of cancer, including prostate cancer and head and neck cancers, while vastly decreasing radiation associated side effects. Stereotactic radiation therapy, which can be delivered via gamma knife, cyber knife or linear accelerators with image guidance, has surged into cancer care. Definitive treatment can be delivered in 1-5 treatments for some types of cancers. In the U.S. 60% of patients with cancer receive radiation therapy as part of their treatment regimen.
These technologies have slowly emerged in veterinary medicine. Starting with the University of Florida frameless high-precision stereotactic radiotherapy system, and then with the emergence of veterinary cyberknife facilities and accelerator based systems with on-board imaging, new technology has impacted veterinary radiation oncology. Now with a substantial number of peer reviewed publications, and many more in the pipeline, it is time to assess the value of this technology. The goal of this SOTA talk is not to discuss technology or biology, but rather outcome data associated with these technologies.

A literature review of published and available unpublished data will review outcome results of commonly irradiated tumors, such as nasal tumors, bone tumors, brain tumors, pituitary tumors and bladder/prostate tumors will be reviewed. Emerging areas of interest, such as bone tumors of the axial skeleton, soft-tissue sarcomas, mast cell tumors, oral tumors, thoracic tumors and heart tumors will also be discussed.
It is equally important to recognize areas where traditional 3D-CRT or point calculated radiation remain firmly entrenched as the standard-of-care. Surgery followed by fractionated radiation therapy continues to be unparalleled for treatment of mast cell tumors, soft tissue sarcomas, and oral tumors. These technologies can also provide cost effective palliative treatments.

As a small specialty community we need to reflect on the appropriate way to communicate to clients and referring veterinarians about which modalities offer the best outcome for their pet and for their family situation.


Learning objective:
• Be able to define and understand the new radiation therapy modalities, including intensity modulated radiation therapy, stereotactic radiation therapy, image guided radiation therapy, and dynamic adaptive radiation therapy.
• Be familiar with what is considered standard of care treatment for common tumor types.
Veterinary Cancer Society

Author Information Play Video Bio

Veterinary Cancer Society
on behalf of Missouri Veterinary Medical Association

Dr. Susan LaRue - Dr. Susan LaRue is originally from Maryland and received her undergraduate education at the University of Maryland. She received her DVM from the University of Georgia, where she also did her internship. She came to Colorado State University in 1983 for a residency in small animal surgery, and subsequently became a Diplomate in the College of Veterinary Surgeons (ACVS). During her surgery residency Dr. LaRue developed a strong interest in oncology. She received her Ph.D. from the (then) Department of Radiological Health Sciences working on tumor cell kinetics in canine osteosarcoma and lymphoma. She also did training in Radiation Oncology under the mentorship of Dr. Edward L. Gillette. Dr. LaRue was a charter Diplomate in the American College of Veterinary Radiology, specialty of Radiation Oncology, and has served as president of that organization.

Dr. LaRue is currently a professor of Radiation Oncology at CSU and head of the Radiation Oncology Service. Her clinical experience combined with her background in radiation biology makes her the ideal person to apply the new technology available on the Trilogy Linear accelerator to veterinary patients. Dr. LaRue’s passion is translational research using naturally occurring tumors in pet animal patients. Our goal is to design studies that help the individual patient as well as provide information to better understand the biology of the cancer.

Current Accreditations

This course has been certified by or provided by the following Certified Organization/s:

  • Missouri Veterinary Medical Association
  • 1.00 Hours -
    Exam Attempts: 3
    Exam Pass Rate: 60

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