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Facing the Challenges of Invasive Fungal Infections: Clinical Updates & Best Practices

Facing the Challenges of Invasive Fungal Infections: Clinical Updates & Best Practices

Facing the Challenges of Invasive Fungal Infections: Clinical Updates & Best Practices

Douglas Slain, PharmD, BCPS, FCCP, FASHP, Melissa D. Johnson, PharmD, MHS, AAHIVP And Ryan K. Shield
Douglas Slain, PharmD, BCPS, FCCP, FASHP, Melissa D. Johnson, PharmD, MHS, AAHIVP And Ryan K. Shield
on behalf of ProCE Inc.

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Launch date: 08 Mar 2017
Expiry Date:

Last updated: 13 Mar 2017

Reference: 170913

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Description

Invasive fungal infections (IFIs) are life-threatening conditions that require astute diagnosis and management to mitigate the high associated morbidity and mortality risks. IFIs are also associated with a high economic burden, owing to prolonged hospitalization, the need for intensive supportive care, and the use of costly new antifungal agents. Opportunistic IFIs occur predominantly in immunocompromised patients, and the incidence of these infections is on a steady increase, as more and more patients undergo surgical procedures, transplantation, or cancer treatment and are receiving immunosuppressive therapies. Several classes of antifungal agents can be used to treat these invasive infections, but some fungi have developed resistance and no longer respond to standard antifungals intended to eradicate them.New therapies offer the potential to improve outcomes for patients with IFIs, but early diagnosis remains a critical component in the effective management of these deadly infections. Clinicians should be aggressive in seeking a diagnosis in patients who are suspected of having an IFI, and the use of available diagnostic tools can improve rates of detection.As medication experts, pharmacists in health-system settings need to assess antifungal use as part of their antimicrobial stewardship programs. This activity will review emerging data and strategies on the diagnosis and pharmacologic management of IFIs, and will use interdisciplinary case examples to demonstrate the clinical application of these principles.

Objectives

Objectives
Learning Objectives:The target audience for this activity includes pharmacists and infectious-disease pharmacists. Upon completion of this activity, participants will be able to:Outline the benefits and limitations of available tools for early diagnosis of invasive fungal infections to select appropriate diagnostic methods.Design guideline-based management strategies for invasive fungal infections, particularly for immunocompromised and immunosuppressed patients, including appropriate prophylactic and empiric treatments.Identify the risks and benefits of new therapies for invasive fungal infections to incorporate them into safe and effective treatment plans.Discuss the role of susceptibility testing and therapeutic drug monitoring in ensuring efficacy and safety of antifungal treatments.
Douglas Slain, PharmD, BCPS, FCCP, FASHP, Melissa D. Johnson, PharmD, MHS, AAHIVP And Ryan K. Shield

Author Information Play Video Bio

Douglas Slain, PharmD, BCPS, FCCP, FASHP, Melissa D. Johnson, PharmD, MHS, AAHIVP And Ryan K. Shield
on behalf of ProCE Inc.

Douglas Slain, PharmD, BCPS, FCCP, FASHP (Chair) Professor Infectious Diseases Clinical Specialist West Virginia University Morgantown, West Virginia Melissa D. Johnson, PharmD, MHS, AAHIVP Associate Professor of Medicine Division of Infectious Diseases & International Health Duke University Medical Center Liaison Clinical Pharmacist Duke Antimicrobial Stewardship Outreach Network Durham, North Carolina Ryan K. Shields, PharmD, MS Assistant Professor of Medicine Division of Infectious Diseases University of Pittsburgh Pittsburgh, Pennsylvania

Current Accreditations

This course has been certified by or provided by the following Certified Organization/s:

  • Accreditation Council for Pharmacy Education (ACPE)
  • 1.50 Hours -
    Exam Pass Rate: 75
    -
    Reference: 0221-9999-16-332-L01-P

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