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IVECCS MDR 2017: Adverse Effects of Fluids

IVECCS MDR 2017: Adverse Effects of Fluids

IVECCS MDR 2017: Adverse Effects of Fluids

Deborah Silverstein, BA, BS, DVM, DACVECC
Deborah Silverstein, BA, BS, DVM, DACVECC
on behalf of Veterinary Emergency and Critical Care Society

$40.00 $ 40.00 $ 40.00


$ 40.00 $ 40.00 $ 40.00
Normal Price: $40.00 FREE


Launch date: 23 Jan 2018
Expiry Date:

Last updated: 16 Jan 2021

Reference: 186176

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Latest User Comments

Steve Amsberry (15 Jan 2021)
Fluids are drugs!
KAREN Fischer (24 Dec 2020)
The information was excellent but the test was ridiculous!
Even listening to the lecture twice and knowing the questions the second time around I still did not get 100%
Taryn Roberts (21 Dec 2020)
Very useful course. Would highly recommend.

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Intravenous fluids are drugs. Like any medication, the potential benefits should always be weighed in light of the possible adverse effects. It is important to realize that the clinical context of a given fluid therapy plan is key to its success or failure. A given fluid strategy that has been proven to benefit one clinical population may lead to increased morbidity in another. Subsequently, recommendations for fluid therapy should be tailored to a tightly defined clinical groups of patients and the stage of their disease process. It is for this reason that fluid prescription must be varied with regards to indications, contraindications and dose ranges based on the individual patient in order to decrease the associated adverse effects. This lecture will review the following:
1. Normal body fluid physiology
2. Critical illness and fluid homeostasis
3. Three major adverse effects of fluids
a. Acid-base derangements.
b. Acute kidney injury
c. Interstitial edema
Although there are many more potential adverse effects of fluid therapy, including thrombophlebitis, hypothermia, coagulopathy and embolism, these will not be discussed in detail in order to focus on the pathophysiology of the aforementioned effects.


Understand normal body fluid physiology
Understand the compartmentalization of fluids in the body and the movement of fluids, electrolytes and macromolecules between compartments. Learn the modified Starling equation and the significance of the endothelial glycocalyx layer.
Understand the derangements in fluid homeostasis in critical illness
Learn the changes in fluid homeostasis secondary to many types of critical illness. Understand both the causes as well as the sequelae of these derangements.
Learn the link between fluid therapy and acute kidney injury
Understand how intravenous fluids can cause acute kidney injury and the causative mechanisms. Both unbalanced crystalloids and synthetic colloids will be the focus.
Understand the mechanism of acid-base derangements
Learn the potential acid-base derangements that can occur secondary to fluid therapy and how they might affect critically ill patients.
Learn how interstitial edema may result from fluid therapy
Understand how fluid therapy can precipitate interstitial edema and its significance in the pathophysiology of organ dysfunction in critically ill animals.
Deborah Silverstein, BA, BS, DVM, DACVECC

Author Information Play Video Bio

Deborah Silverstein, BA, BS, DVM, DACVECC
on behalf of Veterinary Emergency and Critical Care Society

Associate Professor of Critical Care BA, BS, DVM (Univ of Georgia), DACVECC (Univ of CA, Davis) Interests: shock, SIRS/sepsis, fluid therapy, vasopressor therapy, microcirculatory blood flow and perfusion, resuscitation

Current Accreditations

This course has been certified by or provided by the following Certified Organization/s:

  • AAVSB-Registry of Approved Continuing Education (RACE)
  • 1.00 Hours -
    Exam Attempts: 3
    Exam Pass Rate: 70

Faculty and Disclosures

Additional Contributors

Conflicts Declared

Conflicts of Interest declaration by Author:


User Reviews (38)

Go Back
Steve Amsberry (15 Jan 2021)
Fluids are drugs!
KAREN Fischer (24 Dec 2020)
The information was excellent but the test was ridiculous! Even listening to the lecture twice and knowing the questions the second time around I still did not get 100%
Taryn Roberts (21 Dec 2020)
Very useful course. Would highly recommend.
Meg Robinson (15 Dec 2020)
I would like to review the lecture and have access to the notes as I take the exam, open book. Too many y inter
Janet Comeau (16 Nov 2020)
Very academic information - little on practical use of this information
Dr Heather Ludlam DVM (4 Nov 2020)
Heavy on pathophysiology
Mr Bruce Tatton BVSC CertSAS MRCVS (13 Apr 2020)
not as clinical as hoped
Dr Kevin Corr (23 Mar 2020)
Good luck passing the test!
Dr Paige Como DVM (26 Feb 2020)
Heavy on pathophysiology without much discussion on clinical application.
Kate Behnke (19 Feb 2020)
Exam far too academic and difficult.
Dr Byron Misseghers (24 Dec 2019)
NOT RECOMMENDED. This was a very technical presentation with some useful information. However, if you are taking this course for CE credit, the exam process is very detailed and asks questions in a very misleading and purposefully confusing. Even when re-took the course, the answers to the questions are not overtly found in the presentation. Very disappointing CE!
Dr Shannon Klein DVM (22 Sep 2019)
Very in depth science on a microscopic function level with very little take home message as to how to effectively implement change for the better. I attempted to take the test, and no way would I pass. The questions were super in depth and not pertaining to bigger take home message, and the test question format further complicated the ability to answer correctly.
Lisa Carter (10 Sep 2019)
There was a lot of important information in this, but it was overwhelming for just an hour long seminar. The presenter spoke very quickly at times which made it difficult to follow.
Mrs Mallory Olson LVT, VTS(ECC, Nutrition) (23 Aug 2019)
A lot of information with a lot of detail.
Dr Philip DeShield DVM (29 Jul 2019)
Important concept to understand that was well explained but a little rushed.
Michelle Hessell (8 Jun 2019)
To technical
Matthew Hynes (6 Jun 2019)
The examination on this is a little obtuse. I hate answer any/all. So arbitrary.
Dr Mary Cho (31 May 2019)
It was very good that this presentation conveys important new information for patients but it was too challenging to follow due to some factors. The speaker can simplify many biochemistry level of vocabularies into one like EG agents and allow the audience to read the words later as needed. Pronouncing those terminology do not helpful for attention but distract as hypnotic technique does. Also, this lecture requires intense concentration now that any kind of distraction, such as joking, was so disturbing. It was like somebody does gag in the middle of discussion about serious crime scene. Anyway I had to watch this video 4 times to complete my learning.
Merrin Hicks (23 May 2019)
Dr Nancy Matthews DVM (12 May 2019)
Important material
Dr James O'Bryan DVM (26 Apr 2019)
I thought this was going to be a revamp of the same old. A lot of new information presented. I have been able to rethink and modify my treatment approaches.
Joyce Tang (22 Apr 2019)
Good presentation but needs prior background knowledge on ABI, glycocalyx and revised Starling's law to understand the material.
Dr Jessica Kowaleski DVM (14 Apr 2019)
Great speaking skills but the content was extremely technical and I didn't feel like I gained much I could use in day-to-day clinical practice other than a newfound dislike for chloride's presence in most of my fluid choices. The exam was also a bit ridiculously difficult.
Dr Robert Clipsham DVM, PhD (6 Apr 2019)
Great information but far beyond integration in 60 minutes. This is a semester course.
Trudy Salerno (18 Dec 2018)
The speaker spoke so fast it was hard to keep up with the lecture and the use of many acronyms made it difficult to follow.
Dr Dawn Metzger DVM (7 Dec 2018)
Poorly presented, not more than 10% clinically useful. Do not recommend.
Ms Courtney Olson (5 Dec 2018)
It was a lot of information in a short amount of time. It became very over whelming and the test questions felt impossible. It was very advanced for an informational presentation. I feel that it could use condensed content to get the information across better.
Patricia Fritz (2 Dec 2018)
This course was really tough to follow. A lot of info presented very rapidly and the test was made more difficult by having multiple facts within each question.
Dr Jacqueline Myers DVM (2 Dec 2018)
Wayyy too much detail for a GP.
Mary Giles (24 Nov 2018)
Very very technical, which is good in a way, but it would be better if clinical relevance was emphasized more.
Ms Holly Killian CVT (8 Nov 2018)
A lot of information in 1 hour. The speaker started to talk faster as the hour progressed, making it more difficult to follow.
liz stewart (22 Oct 2018)
good information but presented way to fast
bryan hall (27 Sep 2018)
If multiple people that the course is intended for can not pass the exam, it is a reflection of the either the presenter not teaching what they wanted to be tested or the exam not testing what was intended to be taught. Very frustrating. We are brighter than this. I did learn despite the test.
Naomi Hansen (21 Jun 2018)
The course was quite informative but I found the questions at the end difficult to answer despite reviewing the course material on three occasions
Dr Kathryn Downie DVM (19 Jun 2018)
This course was a little over-technical in a biochem way. It was not as practical as I was hoping.
Dr Era Jo Moorer (1 Jun 2018)
Good information.
Mary Ramirez (2 May 2018)
More technical than practical. Exam was extremely challenging. I watched the presentation 3 times and still couldn't pass the exam with a 70%
chris olortegui (24 Apr 2018)
very in depth lecture


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